![]() These are molecules that normally "put the brakes" on your CNS. In simpler terms, caffeine works primarily by binding enzymes and adenosine receptors, thereby blocking their actions. Physiologically, caffeine and its related methylxanthines act as adenosine receptor antagonists, as well as acetylcholinesterase (ACE) and phosphodiesterase (PDE) enzyme inhibitors ( 4 ). As you well know, caffeine is a potent stimulator of the central nervous system (CNS) that induces acute mood-lifting and vigilance-enhancing effects. These natural methylxanthines are all responsible, to varying degrees, for how caffeine works in the body. Hence, very little caffeine ever makes it into the urine. Your body - primarily the liver - actually metabolizes caffeine almost entirely to theobromine, paraxanthine, and theophylline ( 3 ). Other lesser-known methylxanthines found in the typical human diet include theobromine and theophylline. How Does Caffeine Work?Ĭaffeine - or 1,3,7-trimethylxanthine, for the organic chemists out there - is a naturally occurring, alkaline substance that belongs to a group of compounds known as methylxanthines. It’s not entirely clear why this is, but it’s plausible that other compounds in coffee render the caffeine less effective. You might find it surprising that caffeine anhydrous is more effective than drinking caffeine from coffee, particularly for athletic performance ( 2 ). It might help to think of caffeine anhydrous as "caffeine powder" made from natural caffeine. The important thing to grasp is that caffeine anhydrous is the same as "natural caffeine." Caffeine is a discrete chemical - dehydrating it doesn't change how it works in the body. This yields a highly concentrated caffeine powder, and voila! You have caffeine anhydrous. The term "anhydrous" is chemistry lingo for "without water." So, caffeine anhydrous is essentially "dehydrated caffeine." Since caffeine is water-soluble and abundant in certain plants and seeds, especially coffee beans and tea leaves, it naturally exists in liquid phases.ĭuring the caffeine extraction process, it is dehydrated to remove the water content. This guide will show you how caffeine works and set the record straight on these common questions. Moreover, how long does caffeine stay in your system? How much caffeine is too much? All excess chemical components and water are meticulously filtered in the lab, resulting in a purer and more potent form of caffeine. You may notice that some sports supplements, particularly pre-workouts, often contain the ingredient "caffeine anhydrous." But what is caffeine anhydrous, exactly? Is it the same as the caffeine in coffee? What exactly is caffeine anhydrous? Well, it's essentially caffeine extracted from the same plants as regular caffeine but with an added twist. Sure enough, caffeine is the most widely consumed stimulant in the world, being a major constituent of coffee beans and various tea leaves ( 1 ). In recent years, an inordinate amount of "energy drinks" have cropped up in convenience stores and supermarkets across the globe, all of which are fueled by the adrenaline-inducing nootropic we know as caffeine.
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